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Background: Previous studies have reported the associations of frailty phenotype or its components with mortality. However, studies that explored the effects of transition in frailty status on mortality were far less in Asian or Chinese.

The aim of this study was to evaluate baseline frailty status and one-year change of frailty status in relation to all-cause mortality in Taiwanese community-dwelling older adults who participated in the Taichung Community Health Study for Elders. Methods: We conducted a community-based prospective cohort study. A total of community-dwelling elderly men and women aged years in Taichung City were enrolled in and were followed up through We adopted the definition of frailty proposed by Fried et al.

Results: There were deaths during the follow-up period. The mortality rates in groups of robust and frail were After multivariate adjustment, the HR CIs for baseline frailty was 2. Poor endurance and energy [1. Increased risks in mortality for subgroups of robust-to-frail [2. Conclusion: Baseline frailty status and one-year change in frailty status are associated with 6-year all-cause mortality among Taiwanese elderly adults. Frailty may be useful for identifying older adults at high risks for mortality prevention.

Abstract Background: Previous studies have reported the associations of frailty phenotype or its components with mortality. Publication types Research Support, Non-U.