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Methods: Metaphases were analyzed by GTG banding obtained from the culture of lymphocytes of 33 men with idiopathic infertility. Genetic testing can help identify which patients would benefit from technical reproduction. As well as contributing to unraveling the etiology of male infertility in patients treated at LabRep-HC-UFG, this study is relevant because assisted reproduction techniques ignore the process of natural selection and some classic chromosomal abnormalities or deleterious mutations could be inherited.
Thus, counseling based on genetic assessments may prevent the inheritance of primary and secondary congenital defects in the offspring of patients with male infertility.
A unique view on male infertility around the globe. Reprod Biol Endocrinol. Male infertility: biomolecular aspects. Biomol Concepts. Genetic variations and male infertility. London: Academic Press; Chapter 2; p. Chromosomal abnormality in men with impaired spermatogenisis. Int J Fertil Steril. Clinical assessment of the male fertility.
Obstet Gynecol Sci. Chromosomal abnormalities in infertile men from southern India. J Clin Diagn Res. European academy of andrology guideline management of oligo-astheno-teratozoospermia. Chromosomal evaluation in a group of Tunisian patients with non-obstructive azoospermia and severe oligozoospermia attending a Tunisian cytogenetic department.