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Introduction: Cardiovascular parameters characterizing blood pressure BP , heart rate HR , endothelial function and arterial stiffness predict cerebro-cardiovascular events CCVE in the general population. Considering the paucity of data in stroke patients, we assessed these parameters as potential predictors of recurrent CCVE at acute stroke stroke. The study consecutively recruited acute ischemic stroke patients.

Cardiovascular parameters blood pressure variability [BPV], heart rate variability [HRV], endothelial function, and arterial stiffness were assessed within the first week post-stroke.

Future CCVE were recorded over a 3-year follow-up. Multivariate Cox regression analysis was used to investigate the prognostic value of 48 cardiovascular parameters regarding CCVE risk. Results: Out of recruited patients, were included in this analysis. The incidence of cerebro-cardiovascular events CCVE has decreased by nearly half in recent decades, largely due to modifications in cerebro-cardiovascular risk factors 1 , 2.

However, the risk for CCVE remains high in certain populations, such as ischemic stroke patients. Ischemic stroke affects 94 per people per year worldwide 3 , and following a transient ischemic attack TIA or a minor ischemic stroke, 6. This risk escalates to an estimated cumulative rate of Current approaches for the assessment of vascular risk are based on the clinical and laboratory characteristics e.