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Ageing and population shrinking: implications for sustainability in the urban century

Malaria Journal volume 17 , Article number: Cite this article. Metrics details. Malaria is a major cause of anaemia in tropical areas.

Malaria infection causes haemolysis of infected and uninfected erythrocytes and bone marrow dyserythropoiesis which compromises rapid recovery from anaemia. In areas of high malaria transmission malaria nearly all infants and young children, and many older children and adults have a reduced haemoglobin concentration as a result. In these areas severe life-threatening malarial anaemia requiring blood transfusion in young children is a major cause of hospital admission, particularly during the rainy season months when malaria transmission is highest.

In the management of severe malaria transfusion thresholds remain uncertain. Prevention of malaria by vector control, deployment of insecticide-treated bed nets, prompt and accurate diagnosis of illness and appropriate use of effective anti-malarial drugs substantially reduces the burden of anaemia in tropical countries.

Malaria is the most important parasitic disease of man [ 1 ]. It is a major cause of anaemia in endemic areas, and in areas of higher transmission malaria is one of the most common reasons for blood transfusion. Six species of the genus Plasmodium infect humans commonly, and all cause anaemia. Most malaria attributable deaths and severe disease are caused by Plasmodium falciparum. The majority of fatalities occur in the community. The World Health Organization WHO has estimated that there were some million cases and , deaths from malaria in [ 2 ].

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