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Background and Objectives: Pelvic organ prolapse POP is a common condition in women, with its prevalence increasing with age, and can significantly impact the quality of life QOL of many individuals. The objective of this study was to assess the overall improvement, quality of life, and continuation of primary treatment for POP over a month period in a real-world setting.
Materials and Methods: This is a prospective, observational, follow-up study of women with symptomatic POP who, as a primary treatment, opted for recommendations lifestyle changes and pelvic floor muscle training , pessary therapy, or surgery. The primary outcome measure was a subjective improvement at the month follow-up, measured with the Patient Global Impression of Improvement PGI-I scale. Secondary outcome measures were the continuation rate of the primary treatment method, reason for discontinuation, and the quality of life evaluated with the P-QoL questionnaire.
Results: We included women, with 45 women After 24 months, surgery, in comparison with pessary treatment and recommendations, resulted in significantly more women reporting a subjective improvement: However, women who continued the primary treatment, pessary use, and surgery showed similar subjective improvements Conclusions: The chance of significant improvement was higher following surgery.
However, after 24 months, both vaginal pessaries and surgery showed an important quality-of life improvement and can be proposed as primary treatment methods for pelvic organ prolapse.
