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In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript. This was a cross-sectional and a longitudinal, prospective, observational, controlled, quasi-experimental, international multicenter study.

In the cross-sectional cohort, we examined gender proportions at referral, indication evaluations, and DBS surgery. In the longitudinal cohort, clinical assessments at preoperative baseline and 6-month follow-up after surgery included the PD Questionnaire-8, NMSScale, Scales for Outcomes in PD-motor scale, and levodopa-equivalent daily dose.

Propensity score matching resulted in a pseudo-randomized sub-cohort balancing baseline demographic and clinical characteristics between women with PD and male controls. Women with PD were disproportionally underrepresented in referrals compared to the general PD population relative risk [RR], 0. Nonetheless, their total relative risk of undergoing DBS treatment was 0.