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Main outcomes The main outcome measures were the proportion of hospitalisations, virus clearance and the case fatality rate. Results A total of cases The proportion of cases who achieved virus clearance was higher in women Men were associated with a significantly higher risk of dying from COVID than women case fatality rate The mean time, from diagnosis to death, was Conclusions This study suggests that more attention should be paid to sex as a variable for the interpretation of COVID data.

Sex-disaggregated data will help clinicians to make appropriate patient-tailored medical decisions. You will be able to get a quick price and instant permission to reuse the content in many different ways. This study provides sex-disaggregated data of COVID cases at a district level, in Italy, contributing to a better understanding of who is being impacted the most by the pandemic and promoting a patient-tailored treatment approach.

The robust methodology of the present study enabled to accurately correlate the case demographics with COVID clinical response. The data related to the viral clearance, which reflect the diversified course of the disease according to the individual immune response, are confirmatory of sex difference in COVID The data collected are highly homogeneous as they are strictly related to the first epidemic wave and provide an accurate picture of the impact of sex and age on COVID outcomes in Italy during the initial phase of the pandemic.

As the majority of the sex-disaggregated data available in the literature, the data presented in our study are not adjusted for lifestyle, profession, social or behavioural differences. SARS-CoV-2 is a novel coronavirus causing the current pandemic, which has resulted in millions of infections and hundreds of thousands of deaths worldwide.