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Thank you for visiting nature. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser or turn off compatibility mode in Internet Explorer. In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript. The prevalence and antithrombotic treatment of atrial fibrillation AF in Chinese rural population is not well known. Our data indicated the overall prevalence rate of AF was 2.

Of enrolled subjects, Missing early detection In conclusion, most AF patients were with a high risk of thrombosis and a low risk of bleeding in China, but a large majority of them failed to take anticoagulants mainly for missing an early screening of AF and lack of awareness on AF for both patients and primary care physicians.

The number of AF patients is expected to increase 2. Previous studies indicated the prevalence of AF varied greatly among different populations and regions in China 2 , 3 , 4 , 5 , 6. Cardiogenic cerebral embolism has been perceived as the most common and severe complication of AF, which confers high rates of mortality and disability 7. AF increased the risk of stroke by 4—5-fold 1 and This finding highlighted a great gap between current guidelines and the clinical management of AF in China.

The non-vitamin K antagonist oral anticoagulant NOAC has been evaluated in large trials for stroke prevention in AF, which indicated NOAC was non-inferior to warfarin in preventing stroke or systemic embolism, with reducing the risk of life-threatening bleeding 1.