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Current research has mainly focused on vaginal bacterial and fungal members of the community and emphasized their role in disease. However, the impact of balanced vaginal microbiota on health and its interaction with the host is yet poorly understood. High abundance of vaginal lactobacilli is most strongly associated with health, but the concept of health may vary as vaginal dysbiosis may be asymptomatic.
Furthermore, there is a lot of variation between ethnic groups in terms of dominating vaginal bacteria. Probiotic lactobacilli could be a safe and natural means to balance and maintain healthy vaginal microbiota.
This review describes the current literature on vaginal microbiota, the major factors affecting its composition, and how the communities change in different life stages. Furthermore, we focused on reviewing available literature on probiotics and their impact on vaginal microbiota and health. In the past decade, exploration of human microbiota has increasingly focused on vaginal microbiota VMB composition, diversity, and its impact on health, reproduction, and disease.
VMB is known to consist of various bacteria, viruses, archaea, fungi, and protozoa Ursell et al. Typically, VMB is described in the context of vaginal infections or dysbiosis, which occurs, e. Most common infections and conditions include vulvovaginal candidiasis VVC and bacterial vaginosis BV , respectively [reviewed by van de Wijgert and Jespers , De Bernardis et al.
