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To determine whether caffeine may be associated with cognitive decline reduction in elderly at high vascular risk. We ascertained regular caffeine intake at baseline using a validated item-food frequency questionnaire.

From to , we administered four telephone cognitive assessments at two-year intervals evaluating global cognition, verbal memory, and category fluency. The primary outcome was the change in global cognitive score, which was the average of the z-scores of all tests. We used generalized linear models for repeated measures that were adjusted for various sociodemographic, health, and lifestyle factors to evaluate the difference in cognitive decline rates across quintiles of caffeine intake.

Caffeine intake was related to moderately better cognitive maintenance over 5 years in older women with vascular disorders. View our Privacy Policy for more information. Deny Accept. Privacy Preferences.

Essential cookies. Marketing cookies. Personalization cookies. Analytics cookies. Reject all cookies Allow all cookies Save preferences. ISIC Home. Health conditions. Bone health. Coffee and the senses. Green coffee carbon footprint. Regenerative agriculture. Journal of Alzheimers Disease, published online ahead of print. Share this article:. Abstract: Background: Persons with vascular disorders are at higher risk of cognitive decline.