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Metrics details. If at least one interaction, of any type, is listed, then it is included here and compared across the two databases. Results: We included 38 abortives and 23 preventives. Table 1 contains the number of interactions for a given number of medications. Due to hardware limitations, 3 abortives vs.

Conclusion: The likelihood of an interaction increases as the number of combinations of abortives and preventives increases.

This data may help providers to use more rational polypharmacy. Objective: Migraine with aura MwA is associated with a 2-fold risk of ischemic stroke. Higher incidence of atrial fibrillation AF has been demonstrated in MwA compared to Migraine without aura MwoA in longitudinal cohort studies. Patients with AF and inconsistent diagnoses of migraine types were excluded.

The MwA group was significantly older than MwoA This supports that AF-mediated cardioembolism plays a significant role in the MwA-stroke association. Both common and rare genetic variants are believed to underlie the pathophysiology of the prevalent types of migraine, migraine with typical aura and migraine without aura. However, only common variants have been identified so far. Methods: We utilize a systems genetics approach and integrate RNA sequencing data from brain and vascular tissues knwon to be involved in mgriane, and assessed whole genome sequencing of families with clustering of migraine.