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The latest news, analysis and opinion from Cancer Research UK. Anyone can misplace a shoe. Quite often, they would just slip through my hands. The thing taking her body away from her was the treatment. The problem Andrea was — and, to some extent, still is — dealing with is a type of nerve damage called chemotherapy-induced peripheral neuropathy CIPN, or neuropathy from chemo.

The symptoms of neuropathy can range from mild pins and needles to losing all feeling and control of your hands and feet. Chemotherapies are especially good at killing cancer cells, but they can also harm healthy ones. These include the peripheral nerve cells that carry messages back and forth between the brain and spinal cord the central nervous system and the rest of the body.

When peripheral nerve cells are damaged, it becomes harder for the messages to get through. Then the feeling moved up to her hands. But it progressively got worse until it was really overwhelming. Eventually, she began to lose all sense of them at all. Andrea is now cancer-free. She is interested in understanding the complex processes involved in nerve regeneration and investigates how some of them may be important in the development and spread of tumours.

All doctors and patients can do is wait to see if symptoms will appear. Uncertainty like that can make treatment decisions much more difficult. To make things better, we need to find out more about how chemotherapy drugs affect nerve cells. Her investigations have brought an almost unknown system in our bodies into the spotlight. They could give doctors a way to predict, treat and even prevent neuropathy from chemo.