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The artificial tumors were exposed via the three approaches using endoscopic-assisted microneurosurgical technique and neuronavigation. The skull base area exposed and the maneuverability linked to each approach were evaluated using neuronavigation.

Yoshito Otake. Intramembranous bone growth is achieved through bone formation within a periosteum or by bone formation at sutures. Su-tures are formed during embryonic development at the sites of approximation of the membranous bones of the craniofacial skeleton.

They serve as the major sites of bone expansion during postna-tal craniofacial growth. For sutures to function as intramembranous bone growth sites, they need to remain in an unossified state, yet allow new bone to be formed at the edges of the overlapping bone fronts. This process relies on the production of sufficient new bone cells to be recruited into the bone fronts, while ensuring that the cells within the suture remain undifferenti-ated.