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Selective Serotonin Reuptake Inhibitors (SSRIs)

These include:. When the potential benefits e. Your doctor may be using this medication for another reason. If you are unclear why this medication is being prescribed, please ask your doctor. SSRIs are known to increase the amount of a brain chemical called serotonin. It is believed that some brain chemicals, such as serotonin and norepinephrine, are not working well in people who are depressed or overly anxious. The exact way that SSRIs improve the symptoms of depression and anxiety disorders is still not fully known.

Several SSRIs have been studied in children and adolescents diagnosed with an anxiety disorder or depression. When used to treat an anxiety disorder, there is good evidence that SSRIs are more effective than a placebo an inactive pill that looks like medication at decreasing symptoms of anxiety.

Research supports the use of certain SSRIs in children and adolescents with depression. However, some studies in childhood depression have found that certain SSRIs are not better at treating depression symptoms compared to a placebo. Whenever possible, the addition of behavioural therapy such as Interpersonal Therapy IPT for depression or Cognitive Behaviour Therapy CBT to this medication may help to increase the potential for benefit.

In general, for depressed youth who take an SSRI for months, about people out of every 10 who are treated will notice an improvement in their depressive symptoms such as depressed mood, disturbed sleep, changes in appetite, lack of energy, poor concentration and fatigue.

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