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Persons using assistive technology might not be able to fully access information in this file. For assistance, please send e-mail to: mmwrq cdc. Type Accommodation and the title of the report in the subject line of e-mail. Prepared by Cindy M. Mast, MD, Susan A. Neitzel, and John W. Corresponding preparer: Cindy M.
Telephone: ; Fax: ; email: chw4 cdc. This report updates and expands previous CDC guidelines for HBsAg testing and includes new recommendations for public health evaluation and management for chronically infected persons and their contacts. Implementation of these recommendations will require expertise and resources to integrate HBsAg screening in prevention and care settings serving populations recommended for HBsAg testing.
This report is intended to serve as a resource for public health officials, organizations, and health-care professionals involved in the development, delivery, and evaluation of prevention and clinical services. Chronic infection with hepatitis B virus HBV is a common cause of death associated with liver failure, cirrhosis, and liver cancer. Worldwide, approximately million persons have chronic HBV infection, and an estimated , persons die annually from HBV-related liver disease 1,2.
Hepatitis B vaccination is highly effective in preventing infection with HBV and consequent acute and chronic liver disease. In the United States, the number of newly acquired HBV infections has declined substantially as the result of the implementation of a comprehensive national immunization program 3 -- 5. However, the prevalence of chronic HBV infection remains high; in , approximately , Improving the identification and public health management of persons with chronic HBV infection can help prevent serious sequelae of chronic liver disease and complement immunization strategies to eliminate HBV transmission in the United States.