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Federal government websites often end in. The site is secure. Preview improvements coming to the PMC website in October Learn More or Try it out now. Exercise training is commonly recommended for individuals with fibromyalgia. This review is one of a series of reviews about exercise training for people with fibromyalgia that will replace the "Exercise for treating fibromyalgia syndrome" review first published in Other systematic reviews have examined or will examine these comparisons Bidonde ; Busch We included randomized controlled trials RCTs in adults with a diagnosis of fibromyalgia that compared aerobic training interventions dynamic physical activity that increases breathing and heart rate to submaximal levels for a prolonged period versus no exercise or another intervention.
Two review authors independently selected trials for inclusion, extracted data, performed a risk of bias assessment, and assessed the quality of the body of evidence for major outcomes using the GRADE approach. We included 13 RCTs people. We prioritized the findings when aerobic exercise was compared with no exercise control and present them fully here. Effects for aerobic exercise versus control were as follows: HRQL: mean Withdrawals were similar, and investigators did not assess stiffness and adverse events.
Similarly, we are uncertain of the effects of aerobic exercise over active controls ie, education, three studies; stress management training, one study; medication, one study owing to evidence of low to very low quality provided by single trials. Most studies did not measure adverse events; thus we are uncertain about the risk of adverse events associated with aerobic exercise. Three of the reported outcomes reached clinical significance HRQL, physical function, and pain.
We downgraded the evidence owing to the small number of included trials and participants across trials, and because of issues related to unclear and high risks of bias performance, selection, and detection biases.
