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Here, we investigated the relationship between mean nocturnal RR and mortality in community-dwelling older men and women. One hundred sixty-six men 6. All-cause mortality was Whether nocturnal mean RR can be used as a risk marker warrants further prospective studies. Respiratory rate RR is one of the four vital signs along with heart rate, arterial blood pressure, and core temperature. In particular in older people [ 1 ], RR strongly predicts short-term in-hospital mortality [ 2 , 3 ] in patients in the setting of pneumonia [ 4 ], trauma [ 5 ], stroke [ 6 ], cardiac arrest [ 7 ], and acute heart failure [ 8 ].

RR is typically measured by counting the number of breaths for one minute. In adults at rest, any RR between 12 and 20 breathes per minute bpm is considered normal; tachypnea is defined as RR greater than 20 bpm [ 9 ]. RR may increase with acute pathological conditions like fever, compensation for diabetic ketoacidosis or decompensated acute heart failure.

Chronic pathophysiological conditions like decompensated kidney disease, heart failure or chronic obstructive pulmonary disease may also result in RR changes. While elevated blood pressure [ 10 ] and increased heart rate [ 11 ] are well-recognized risk factors for long-term CV morbidity and mortality in the general population, the association between RR and long-term CV outcomes is unclear.