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Thank you for visiting nature. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser or turn off compatibility mode in Internet Explorer. In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript. Post-operative anaemia is linked to iron deficiency.
We investigated the prognostic value of post-operative iron biomarkers in colorectal cancer CRC. After a median follow-up of 9. Similar but weaker associations were observed for OS.
Future studies should validate our findings. Colorectal cancer CRC is the second leading cause of cancer-related mortality and the third most diagnosed cancer worldwide [ 1 ].
The prognosis of CRC patients is worse for patients with advanced cancer stage at diagnosis [ 2 ], which underscores the need for refined screening and treatment strategies towards improving outcomes. Although a number of modifiable and non-modifiable prognostic factors have been reported for patients with operable CRC, there remains a substantial unexplained variation in post-operative clinical outcomes, such as survival, tumour recurrence, and progression [ 3 ].